Author: Stuart Goldman, MD

Much ado about (almost) nothing: Revisiting Paxil in adolescents

adolescent brain Paxil
(anton_novik/Shutterstock)

BMJ recently published a re-analysis of a 2001 study published in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), evaluating the use of paroxetine (Paxil) to treat teens with depression. This re-analysis falls under the RIAT (restoring invisible and abandoned trials) initiative that encourages companies and researchers to update findings from past clinical trials.

This news is essentially “much ado about nothing,” because no one was doing anything based upon the 2001 study. But it is worth noting because it was not the best moment for the JAACAP and the authors of the original article. …Read More

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