Paper Trail: Fever in children, early ACL reconstruction, hydrocephalus and more

Boy looking at medical scale

Boston Children’s Hospital is at the forefront of clinical research. Stay connected with Paper Trail — a monthly feature highlighting recently published outcomes data and new approaches to the diagnosis, treatment and prevention of pediatric illnesses.

Fever in Children: Pearls and Pitfalls

Fever in children is a prominent concern for parents and a frequent cause of emergency department visits. Although in most instances the cause of these fevers is a mild viral illness, some children might be at risk of a more serious, life-threatening infection. Emergency Medicine researcher Baruch Krauss, MD, EdM writes about the epidemiology, measurement, meaning and clinical signs of a fever in a pediatric patient, learn more in this Children paper.


Prevention, treatment, and rehabilitation of anterior cruciate ligament injuries in children

As the number of children and teens participating in competitive sports is increasing, so is the frequency of anterior cruciate ligament (ACL) injuries. Historically, treatment would consist of rehabilitation until the patient reached skeletal maturity, then modification would take place; however, Lyle Micheli, MD, director of our Sports Medicine Division writes that more recent evidence encourages early reconstruction. Read more about the complexities in ACL injury treatment, re-tear prevention and the debate between early and delayed modification in this Open Acess J Sports Med article.


Utilizing trauma admissions as an opportunity to identify developmental and behavioral concerns

In the pediatric population, developmental and behavioral problems tend to be underdiagnosed, and can be risk factors for injury and trauma. In a study titled “The Survey of Wellbeing of Young Children,” researcher Catherine Chen, MD, MPH assessed the opportunity that pediatric trauma admissions provide to screen patients for these developmental and behavioral concerns. Read more about their research in the American Journal of Surgery.


Growing Brains: How Adapting to Africa Advanced the Treatment of Infant Hydrocephalus

Infant hydrocephalus is an under-recognized yet prominent global health problem, with over 400,000 new infant cases a year. Of those cases, 100,000 come from Sub-Saharan Africa alone, making it a key region to analyze the pathogenesis in order to develop public health strategies for prevention. Read more about hydrocephalus and its treatment in this Clinical Neurosurgery paper written by Benjamin C. Warf, MD, Director of our Neonatal and Congenital Anomaly Neurosurgery Program.


Disparities in epilepsy surgery in the United States of America

Tobias Loddenkemper, MD alongside other neurology researchers conducted a study to describe the epidemiology of epilepsy surgery. By analyzing the National Inpatient Sample and the Kids’ Inpatient Sample, researchers found racial disparities in both pediatric and adult admissions, more specifically an underrepresentation of Blacks in both patient pools. Find out more about their results by reading this Journal of Neurology article.

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