Paper Trail: Pneumonia, cystic fibrosis, intestinal-failure outcomes data and more


Boston Children’s Hospital is at the forefront of clinical research. Stay connected and read about some of our recently published clinical research in Paper Trail — a timely and informative feature highlighting outcomes data and new approaches to the prevention, diagnosis and treatment of pediatric illnesses.

This edition of Paper Trail focuses on intestinal-failure outcomes data, pneumonia-examination accuracy data, sexual and reproductive health behaviors of young women with cystic fibrosis, and trends in Medicaid-insured children with high frequency Emergency Department use.

Intestinal failure is complex but survivable in most children

Once almost always fatal, pediatric intestinal failure is now survivable in more than 90 percent of cases. A combination of innovative medical, nutritional and surgical approaches for this condition, all provided in a multidisciplinary program, are the key reasons why.  Christopher Duggan, MD, MPH, and Tom Jaksic, MD, PhD, at Boston Children’s Center for Advanced Intestinal Rehabilitation offer expert insight in a recent review article in the New England Journal of Medicine.

Does this child have pneumonia? 

Accounting for 900,000 lives worldwide, pneumonia is the leading cause of mortality and morbidity in children after the neonatal period. In hopes of improving diagnosis time and reducing morbidity and antibiotic overuse, Sonal Shah, MD, MPH, Richard G. Bachur, MD, and Mark Neuman, MD, MPH, of the Emergency Medicine Department at Boston Children’s Hospital, analyzed the accuracy of examinations and symptoms in pediatric patients. Read about their findings in The Journal of the American Medical Association (JAMA).

Sexual and reproductive health behaviors and experiences reported by young women with cystic fibrosis 

As treatments improve and people with cystic fibrosis (CF) live longer and healthier lives, they are increasingly faced with sexual and reproductive health (SRH) decisions. How are the SRH behaviors and experiences of young women with CF unique? Do they have specific health care needs and are they being addressed? This study published in the Journal of Cystic Fibrosis by a Boston Children’s Pediatric Health Services Research Fellow Traci Kazmerski, MD, MS, aims to find out. Read the paper.

Characteristics of children enrolled in Medicaid with high-frequency Emergency Department use

In 2012, children accounted for 25 percent of emergency department (ED) visits, many insured by Medicaid. Finding trends in Medicaid-insured children with high frequency ED use could lead to more targeted and effective interventions. Read the study authored by Jay Berry, MD, MPH, and Mark Neuman, MD, MPH, from Boston Children’s General Pediatrics and Emergency Medicine Departments and published in Pediatrics, and learn how identifying demographic and clinical characteristics of pediatric patients at risk of sustained high ED use could affect child health policy and clinical practice.

For more clinically-actionable insights, bookmark Boston Children’s Notes blog for primary care providers.