Stories about: Bone Marrow Failure and Myelodysplastic Syndrome Program

Expert’s Corner: Evaluating a child for possible bone marrow failure syndrome

Bone marrowPediatricians face a difficult task determining when to refer a child for a suspected bone marrow failure syndrome. These syndromes are a group of disorders that typically share a few common features: low blood counts due to poor blood cell production, congenital anomalies and cancer predisposition. However, only a subset of children with bone marrow failure syndromes will present with the findings described in textbooks. These children often appear well and lack classical physical findings. The blood counts may even sometimes be normal or only drop intermittently, but remain at risk for malignancy. By the time a child looks sick, their marrow’s ability to produce blood cells can be so weakened that it could be too late – or at least much more difficult – to treat them successfully. …Read More