Stories about: hepatitis C

Hepatitis C is on the rise among adolescents. Where do new antivirals fit in the treatment picture?

liver hepatitis C antivirals adolescents

Direct-acting antiviral drugs like sofosbuvir have provided amazing (albeit very expensive) outcomes in patients with hepatitis C (HCV), with cure rates approaching 90 percent. Can these medications—which promise a rapid cure of HCV, as opposed to long-term management of the virus and its complications—do the same for children?

The answer is, we don’t yet know. We need to figure it out quickly, though, because as Gastroenterology & Endoscopy News (G&EN) reports, doctors are seeing a surge of HCV cases associated with injection drug use among adolescents and young adults.

But we may have more information soon. Maureen Jonas, MD, clinical director of the Center for Childhood Liver Disease at Boston Children’s Hospital, tells G&EN that pediatric studies of these drugs are ongoing. …Read More

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C Tracker app brings hepatitis C research to the iPhone, and to patients

Early Monday morning Boston Children’s Computational Health Informatics Program (CHIP) flipped the switch to release C Tracker, the group’s first ever app to run on Apple’s ResearchKit system for clinical research. The app lets people living with hepatitis C track their health, medication use and quality of life over the course of months or years.

But it’s about more than health tracking; it’s about lowering barriers and making it easier for patients to participate in population-scale outcomes research on hepatitis C medications and how they respond to those medications in the real world. As CHIP director and C Tracker lead Ken Mandl, MD, MPH, said in a statement:

“Traditional clinical trials are plagued by abysmal accrual rates, slowing progress in discovering cures. We foresee a future where ResearchKit apps like C Tracker lower the barrier to participation and speed medical progress.

By and large, the data we have now about hepatitis C treatments come from traditional clinical trials. With C Tracker, we can listen to the patient voice to learn how people live with hepatitis in the real world.”

C Tracker is available as a free download on the iTunes App Store. You can learn more about the research the app supports at

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