Stories about: Peter Manley

The time is now: Reducing the toxicity of cancer treatment

infusion pump chemotherapy cancer treatment survivorship
(Pruit Phatsrivong/Shutterstock)

Looking back over the last half a century—maybe not even that long—one can see how the conversation about treatment in pediatric oncology has evolved. It used to be that survival rate was the primary, maybe only, concern among pediatric oncologists. How can we help more children and achieve more cures?

Fast forward to today. With experience and experiment has come greater knowledge of the biology underlying many solid, neurological and hematologic malignancies. That knowledge has, in turn, opened opportunities to reduce the long-term toxicity of cancer treatment and improve survivorship along with survival. How can we help more children survive, and survive better?

“These discussions are no longer in the background. They’re right up front,” says Elizabeth Mullen, MD, of Dana-Farber/Boston Children’s Cancer and Blood Disorders Center‘s Solid Tumor Center. “There’s much more focus on avoiding late toxicities because of the success rates that we see. It’s so much more of how we think now, even when we’re treating high-risk disease. It’s always part of the conversation.”

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Tips when caring for childhood cancer survivors

childhood cancer survivor pediatrician

As more and more children survive cancer, it is estimated that 1 in 300 young adults is a childhood cancer survivor. These survivors are returning in ever-greater numbers to their primary care providers (PCPs) for their ongoing care. PCPs may be challenged in caring for these survivors, because they were treated with many different therapies associated with rare, but significant, complications or “late effects.”

Lisa Diller, MD, chief medical officer of Dana-Farber/Boston Children’s and medical director of the David B. Perini, Jr. Quality of Life Clinic, spoke to MedPageToday about her five top tips for adult or family PCPs managing the care of adult patients who survived childhood cancer.

Below, Diller and Peter Manley, MD,a Dana-Farber/Boston Children’s neuro-oncologist and director of the Stop & Shop Family Pediatric Neuro-Oncology Outcomes Clinic, share their recommendations for pediatricians seeing cancer survivors who are still in their childhood or adolescent years. …Read More

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