
Urinary tract infections affect approximately 3 percent of children in the United States and account for more than 1 million visits to pediatricians’ offices every year.
Although antimicrobial prophylaxis has been proven effective in preventing recurrent UTI in children specifically with vesicoureteral reflux, there remains an increased antibiotic resistance in children treated with antibiotics.
A recent study titled “Antimicrobial Resistance and Urinary Tract Infection Recurrence” sought to further investigate the relationship of antibiotic use and antibiotic resistance among children with vesicoureteral reflux. The paper, published in Pediatrics by the American Academy of Pediatrics (AAP), shows that although resistance was more common among children on antibiotic prophylaxis, antibiotic resistance decreased the longer the children stayed on prophylaxis.
This surprising finding suggests that children who require extended prophylaxis may not be at as high a risk of resistant infection as commonly thought.
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